Clinical Studies & Articles

Explore Cutting-Edge ASI Clinical Studies

Digital imaging correlation of immunohistochemistry and fluorescence in situ hybridization in breast carcinoma cases with HER2 genetic heterogeneity

Genetic heterogeneity is a rare but important event in the evaluation of HER2 amplification status. In this study, the authors investigated whether HER2 fluorescence heterogeneity correlated with increased protein expression by (IHC) and/or morphologic features using image analyses.

Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines

Renal Cell Carcinoma is on the top 10 of the most incident cancers worldwide, being a third of patients diagnosed with advanced disease, for which no curative therapies are currently available.

High Expression of PD-L1 Is Associated with Better Survival in Pancreatic/Periampullary Cancers and Correlates with Epithelial to Mesenchymal Transition

Periampullary cancers are characterized by tumor-infiltrating lymphocytes, severe fibrosis, and epithelial to mesenchymal transition. The immune checkpoint marker programmed death-1 (PD-1) and its ligands 1 and 2 have gained popularity in cancers with TILs.

Comparison of Ki-67 Labeling Index Patterns of Diffuse Large B-Cell Lymphomas and Burkitt Lymphomas Using Image Analysis: A Multicenter Study

Diffuse large B-cell lymphoma (DLBCL) is the most common high-grade B-cell lymphoma
found in Korea; it manifests with a variety of cellular morphologies and a high proliferation index.