Explore Cutting-Edge ASI Clinical Studies
The development of medicinal products often continues throughout the different phases of a clinical study and may require challenging changes in raw and starting materials at later stages. Comparability between the product properties pre- and post-change thus needs to be
In this article, the authors studied cytogenetics and molecular genetic profile in pediatric B-acute lymphoblastic leukemia (ALL) and correlate it with induction outcomes. G-banded karyotyping was used to assess bone marrow specimens.
Genetic heterogeneity is a rare but important event in the evaluation of HER2 amplification status. In this study, the authors investigated whether HER2 fluorescence heterogeneity correlated with increased protein expression by (IHC) and/or morphologic features using image analyses.
Renal Cell Carcinoma is on the top 10 of the most incident cancers worldwide, being a third of patients diagnosed with advanced disease, for which no curative therapies are currently available.
Periampullary cancers are characterized by tumor-infiltrating lymphocytes, severe fibrosis, and epithelial to mesenchymal transition. The immune checkpoint marker programmed death-1 (PD-1) and its ligands 1 and 2 have gained popularity in cancers with TILs.
Diffuse large B-cell lymphoma (DLBCL) is the most common high-grade B-cell lymphoma
found in Korea; it manifests with a variety of cellular morphologies and a high proliferation index.