Validation of MYC and BCL6 rapid break apart digital fluorescence in situ hybridization assays for clinical use

Detection of gene rearrangements in MYC and human B-cell lymphoma 6 using fluorescence in situ hybridization (FISH) are important in the evaluation of lymphomas, in particular diffuse large B-cell lymphoma and Burkitt lymphoma. Together with advances in FISH methodologies, implementation of digital analysis systems introduces significant improvement to the clinical workflow and patient care.

For the full article –