MYC protein is a high-risk factor in mantle cell lymphoma and identifies cases beyond morphology, proliferation and TP53/p53 – a Nordic Lymphoma Group study

The transcription factor MYC is a well-described oncogene with an important role in lymphomagenesis, but its significance for clinical outcome in mantle cell lymphoma (MCL) remains to be determined. In this study, the authors report the investigation of the protein expression of
MYC in a cohort of 251 MCL patients.
Digital FISH was used to assess tumor areas.

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