High Expression of PD-L1 Is Associated with Better Survival in Pancreatic/Periampullary Cancers and Correlates with Epithelial to Mesenchymal Transition

Periampullary cancers are characterized by tumor-infiltrating lymphocytes, severe fibrosis, and epithelial to mesenchymal transition. The immune checkpoint marker programmed death-1 (PD-1) and its ligands 1 and 2 have gained popularity in cancers with TILs. In this study, the authors evaluated the expression and prognostic significance of immune checkpoint and EMT markers in periampullary cancers using automated image analysis.

For the full article – https://pubmed.ncbi.nlm.nih.gov/33810560/