Acute leukaemia is a heterogeneous neoplastic disease that occurs by the growth of abnormal lymphoid and myeloid cells in the bone marrow and blood leading to acute myeloid leukaemia (AML) and acute lymphocytic leukaemia (ALL). In this article, the authors use karyotyping to detect chromosomal abnormalities in AL and confirm specific chromosomal abnormalities using FISH, arguing that despite other advanced molecular techniques in diagnosing neoplasms, conventional cytogenetics remains the baseline.
For the full article – https://pubmed.ncbi.nlm.nih.gov/37728468/