Knowledge Center – Webinars

Cytogenetics in the diagnosis of AML

May 18, 2021

About the Webinar: Whilst cytogenetics is considered by some to be an outdated diagnostic tool, it is still of prime importance in the diagnostic testing of haematological malignancies. This talk will provide a basic introduction to the processes used in cytogenetic analysis, discuss how these are used in our laboratory, and their importance in the diagnosis of Acute myeloid leukaemia.

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Pluripotent Stem Cell Differentiation Webinar

April 21, 2021

About the Webinar: The manufacturing of human induced pluripotent stem (iPS) cell lines according to clinical standards is fundamentally important for autologous and allogeneic regenerative therapies globally. The unique features of our manufacturing process are 1. the use of fibroblasts as a starting material, as apposed to blood mononuclear cells used by other programs, which could better support neuronal differentiation; 2. the use of mRNAs to transiently express reprogramming factors, as apposed to use of viruses by other programs, which create high risk; and 3. we selected several donors that are collectively immunologically matched to dozens of mullions of individuals from European ancestry. During the lecture, we will explain the principles of risk assessment that guide the qualification of reagents, instruments, and processes for the manufacturing of clinical grade human iPS cells under GMP standards. We will furthermore illustrate the criteria that underlie healthy donor selection and tissue procurement for the generation of human iPS cells that can be used as starting material in cellular therapies. Finally, we will explain critical regulatory considerations in the manufacturing of iPS cells and their differentiation for creating clinical grade cell products

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Digital Cell Analysis Tools – Educational Webinar

April 21, 2021

About the Webinar: This webinar is an overview of the subject matter of digital cell analysis and the company ASI. If you want to delve deeper into any of the applications discussed today, we have dedicated solutions and webinars for each product. Today we will provide an overview of ASI, so you may get to know who we are, what we do and what we offer to the medical community

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Integrated Solutions in Digital Pathology – Webinar

April 21, 2021

About the Webinar: This webinar will discuss current digital analysis instrumentation for cancer diagnosis, in-depth cell analysis and beyond. Learn how digital platforms enable labs to increase sample turnaround time, increase accuracy, digitize slides and so much more. With computer assisted analysis, more regions of interest can be accounted for, providing greater statistical results.

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Utilizing FISH Technology in Cancer Analysis and Aneuploidy

April 21, 2021

About the webinar: Genome instability leading to genome rearrangements and aneuploidy is a hallmark of cancer and is found in ~90% of solid tumors. Aneuploidy, the most deleterious form of genomic instability, is detrimental for normal cells. Analysis of CIN in premature senescence in human primary fibroblasts using a variety of stressors reveals common patters of aneuploidy. During the presentation we will discuss experimental approaches and challenges associated with the analysis of aneuploidy in non-tumor tissues and present approaches to overcome the difficulties associated with measuring low frequency aneuploidy.  

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