Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines
Renal Cell Carcinoma (RCC) is on the top 10 of the most incident cancers worldwide, being a third of patients diagnosed with advanced disease, for which no curative therapies are currently available. Thus, new effective therapeutic strategies are urgently needed.
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Simultaneous analysis of ALK, RET, and ROS1 gene fusions by NanoString in Brazilian lung adenocarcinoma patients
Gene fusions have been successfully employed as therapeutic targets for lung adenocarcinoma. However, tissue availability for molecular testing of multiples alterations is frequently unfeasible. We aimed to detect the presence of ALK, RET, and ROS1 rearrangements by a RNA-based single assay in Brazilian lung adenocarcinomas and to associate with clinicopathological features and genetic ancestry.
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The Benefits of Digital Diagnostics Applies to Multi Species As Well
About veterinary pathology and how it can benefit from digital diagnostic integrations throughout the laboratory workflow process. Applied Spectral Imaging provides multi-species digital diagnostic solutions in both chromosome analysis such as G-band testing and pathology analysis such as H&E, IHC and FISH testing.
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Interview with pathologist Dr. Michael Misialek
The purpose of this interview is to expose more people to the field of pathology, increase awareness of new clinical support tools and, provide educational content that is of value to patients and the healthcare community.
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Quantitative Histopathology Analysis
Advancements in digital pathology can increase turnaround time, improve accuracy by accounting for thousands of cells and classify cells in real time. Nevertheless, these tools keep the pathologist and scientific experts at the forefront as they can overwrite and modify every step of the analysis process. These support tools help with the interpretation of data and visualization of slides, not finalizing a diagnosis.
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