RNDr. Jiří Horáček will present the Cytogenetic Laboratory Gennet, its background and the range of methods in use. RNDr. Jiří Horáček will explain the reasons which led to the introduction of automatic scanning and karyotyping, the procedure of this implementation and the method of using the system. Finally, he will show a few cases illustrating the use of karyotyping with GenASIs in the context of other cytogenetic/cytogenomics methods.